StatuManu has identified an important connection between the eye, the brain and the vessels, namely that these function as measurement tool for ICP.
An increasing width of the vessels in the eye is an indication that the pressure in the brain is increasing. As arteries and veins are observable on the fundus of the eye with a camera and a special lens, StatuManu has developed a solution to accurately estimates changes in ICP by measuring the diameter of the vessels.
With this discovery, the utilisation of a fundus camera and measuring the diameter of the vessels, both veins and arteries, multiple times over a short period of time, it is possible to predict changes in ICP.
The ICP Tracker shall be able to measure variation in ICP within +/- 4 mmHg in 80% of the measurements in the range of changes from -30 to +30 mmHg.
ARE YOU INTERESTED IN ICP?
If you are interested in a conversation about StatuManu ICP, research or potential clinical studies, feel free to reach out to firstname.lastname@example.org. Health care professionals are incredible valuable to the device and its dispersion, so we would be very excited to hear from you.
The normal range for ICP varies with age. Normal values are 5-15 mmHg for adults and older children, 3-7 mmHg for young children, and 1.5-6 mmHg for new-borns.
In healthy adult humans with closed cranial fontanels, of which the anterior closes as the last one at about the age of 26 months, the central nervous system; brain, spinal cord, and blood and cerebrospinal fluid (CSF), is confined in a non-compliant compartment of the skull and spinal canal.
As the Monro-Kellie doctrine describes, any increase in the volume of its contents will increase the pressure within the cranial vault. The Monro-Kellie doctrine explains that the sum of intracranial volumes of brain, CSF, and blood is constant, and that an increase in any one of these must be offset by an equal decrease in another, or else intracranial pressure rises.
The threshold for intracranial hypertension varies throughout the literature, as well as in clinical practice. Generally, ICP above 20 mmHg is referred to as elevated. Often, ICP higher than 20-25 mmHg requires treatment to reduce ICP. Similarly, persistent ICP values greater than 40 mmHg indicate severe, life-threatening intracranial hypertension.